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Methadone, sold under the brand name Dolophine among others, is an opioid used to treat pain and as maintenance therapy or to help with tapering in people with opioid dependence.
Formula: C21H27NO Excretion: Urine, faeces
Bioavailability: 41–99% (by mouth) Onset of action: Rapid
Trade name: Dolophine, Methadose, others
Metabolism: Liver (CYP3A4, CYP2B6 and CYP2D6-mediated)
Biological half-life: 15 to 55 hours
Sometimes an opioid is called a narcotic. Methadone also reduces withdrawal symptoms in people addicted to heroin or other narcotic drugs without causing the “high” associated with the drug addiction. Again, methadone is used as a pain reliever and as part of drug addiction detoxification and maintenance programs. Methadone is one of a number of synthetic opiates that are manufactured for medical use and have similar effects to heroin and morphine.
Methadone is mainly used today as a substitute for heroin, in an attempt to relieve some of the problems associated with heroin addiction.
How should I use methadone?
Methadone may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE OF NARCOTIC MEDICATION CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Selling or giving away methadone is against the law.
Follow all directions on your prescription label. Methadone can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never use in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Dissolve the dispersible tablet in at least 4 ounces of water, orange juice, or other citrus-flavored non-alcoholic beverage. Allow the tablet to disperse in the liquid. The tablet will not dissolve completely. Drink this mixture right away. To get the entire dose, add a little more water to the same glass, swirl gently and drink right away.
Never use methadone tablets or liquid to make a mixture for injecting the drug into your vein. This practice has resulted in death with the misuse of methadone and similar prescription drugs.
When used as part of a treatment program for drug addiction or detoxification, your doctor may recommend that each dose be given to you by a family member or other caregiver.
Additional forms of counseling and/or monitoring may be recommended during treatment with methadone. You should not stop using this medicine suddenly. Follow your doctor’s instructions about tapering your dose. buy methadone online – methadone sales – buy fentanyl – buy drugs online
Store at room temperature away from moisture and heat. Keep the medication in a place where others cannot get to it.
Methadone is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.
Do not keep leftover methadone pills or liquid. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take- back program, flush any unused pills or liquid medicine down the toilet. This advice applies to a very small number of medicines only. The FDA, working with the manufacturer, has determined this method to be the most appropriate route of disposal and presents the least risk to human safety. buy methadone online – methadone sales – buy fentanyl – buy drugs online
What are the immediate effects of taking methadone?
Methadone has a similar effect to that of opiates but not as intense. More so Methadone produces a mild sense of well-being, relaxation and detachment. Also Methadone stops physical and psychological pain. The effects last longer than heroin and the sense of well-being can last for up to 24 hours. buy methadone online – methadone sales – buy fentanyl – buy drugs online
Some people are sick when they take drugs like methadone for the first time. It can also cause a loss of sex drive and back pain. buy methadone online – methadone sales – buy fentanyl – buy drugs online
What are the long-term effects of taking methadone?
Methadone doesn’t deliver the same degree of buzz as heroin but it is addictive. There can be some withdrawal symptoms but they are usually much less severe than what occurs when stopping heroin. buy methadone online – methadone sales – buy fentanyl – buy drugs online. Buy pain pills online
What class drug is methadone?
Methadone is a class A drug. It is only legal for a person to possess methadone if he/she has prescriptions for the drud. The maximum sentence for unlawful possession is 7 years imprisonment and a fine. The maximum sentence for supplying is life imprisonment and a fine. buy methadone online – methadone sales – buy fentanyl – buy drugs online
Before using methadone
You should not use methadone if you are allergic to it, or if you have:
- severe asthma or breathing problems; or
- a bowel obstruction called paralytic ileus.
Methadone may cause a life-threatening heart rhythm disorder. Your heart function may need to be serious watch during treatment. buy methadone online – methadone sales – buy fentanyl – buy drugs online. Buy pain pills online
Some medicines can interact with methadone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications. Buy pain pills online
To make sure this medicine is safe for you, tell your doctor if you have:
- heart disease, a heart rhythm disorder, or a personal or family history of long QT syndrome
- any type of breathing problem or lung disease
- a history of head injury, brain tumor, or seizures;
- a history of drug abuse, alcohol addiction, or mental illness
- liver or kidney disease
- urination problems; or
- problems with your gallbladder, pancreas, or thyroid.
This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant. buy methadone online – methadone sales – buy fentanyl – buy drugs online – Buy pain pills online
Methadone can pass into breast milk and may cause breathing problems or addiction and withdrawal symptoms in a nursing baby. Tell your doctor if you are breast-feeding a baby. Buy pain pills online